The founder Kavi Gupta established his namesake gallery in 2000, in the West Loop neighborhood of Chicago. Today, they operate multiple museum-quality exhibition spaces at 835 W. Washington Blvd. and 219 N. Elizabeth St. in Chicago, and 219/215 E. Buffalo St. in New Buffalo, Michigan, as well as a large-scale warehouse and conservation center and a dedicated space for research and archives. The publishing imprint, Kavi Gupta Editions, designs and publishes high-quality monographs, exhibition catalogues, artist editions, and academic texts, while regularly partnering with institutions and such art publishing leaders as Skira, Mousse, Phaidon, and DAP.

In addition to hosting more than a dozen major exhibitions each year, and participating in vital international art fairs such as Frieze New York and London, Frieze Masters, Art Basel Miami Beach, Art Basel Hong Kong, EXPO Chicago, and the New York Armory Show, they host artist talks, facilitate special programming in support of philanthropic causes, and foster intellectual discourse by regularly bringing artists, curators, and collectors together with academics and experts in the contemporary art field.

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